Find out why Advanced Powder Dynamics is your next liquid to powder solutions partner.

Cyclodextrin Inclusion & Encapsulation Experts

Advanced Powder Dynamics is a leader in providing cyclodextrin encapsulation technology. The unique access to CyLoc® encapsulation and delivery system improves the stability and targeted release of individually packaged active ingredients in a powdered product. This technique has specific formulations to fit the needs of each product to improve and enhance their effects. 

Tesseract-CyLoc
colorful tes tubes

Unlock the Power of Cyclodextrin Microencapsulation

Improve stability, solubility, absorption, and bioavailability of your active molecules

  • Stability: lowers effects of pH, metabolism, and inherent chemical instability 
    • Keeps products in good condition during the drying process
    • Maintains efficiency during its intended use
    • Longer shelf life
  • Solubility: increases water solubility 
    • Better release throughout the body
  • Absorption: delivers active molecules to desired location for targeted release
    • Cleaner product
    • Less contamination
    • Faster effective outcome
  • Bioavailability: individualized molecules in a stable environment increases longevity and efficacy

Cyclodextrin Inclusion Complex

Cyclodextrin microencapsulation surrounds individual organic molecules inside a ring of starch fibers. 

  • Cyclodextrin itself is composed of repeating glucose monosaccharides connected in a ring of varying units. 
  • The size of the ring depends on the number of glucose units (α-CD = 6 units, β-CD = 7 units, and γ-CDs = 8 units). This forms a 3-dimensional hollow shape of an open, tapered cylinder. 
  • The center of the cyclodextrin ring is water-resistant, which is compatible with most organic molecules, and the exterior prevents degradation during the drying process.
  • Encapsulation does not alter the chemical ingredients of the product in any way, and maintains the integrity of each molecule while separating them individually for drying, long term storage, and targeted release

Specialized Microencapsulation Technology

At Advanced Powder Dynamics, we are proud to provide expertise in Tesseract proprietary Inclusion and Delivery Technology known as CyLocⓇ. This cyclodextrin microencapsulation technology provides a CyLoc® cyclodextrin layer surrounding each active molecule. Tesseract Medical Research aligns with our promise to deliver high-quality powdered products with strengthened protection and improved release methods. Here’s how it works:

  • The CyLoc® cyclodextrin layer protects sensitive active molecules from harmful factors during the drying process such as heat, pH, light, and chemical oxidation.
  • Cyclodextrin is insoluble in water and under most digestive conditions, allowing increased delivery of organic molecules throughout the body. When the microencapsulated molecule reaches its destination, the Dextrin® reactor becomes activated to break down the CyLoc® insoluble layer to release its cargo. 

See APD in Action

Valensa needed a cyclodextrin expert to support the production of high-quality saw palmetto ingredients for use across food, beverage, and supplement applications. APD’s expertise in cyclodextrin inclusion and dynamic atomization technology made them uniquely qualified for this challenge.

A close-up of saw palmetto leaves

Active Molecules for Cyclodextrin Microencapsulation

💊 Pharmaceuticals: longer shelf life, improved release

🧴 Cosmetics & Personal Care: greater stability without harmful contaminants

🌿 Dietary Supplements & Nutraceuticals: longer shelf life, improved release, elimination of tastes and odors

🌽 Food & Flavoring for Humans and Animals: removal of dyes and harmful contaminants

Advanced Powder Dynamics maintains a working portfolio of 350+ ingredients and organic compounds to meet customer needs with the ability to expand. 

A DA-500 Dynamic Atomization dryer

Benefits of Cyclodextrin Microencapsulation

Our cyclodextrin microencapsulation services provide additional benefits to food and pharmaceutical inclusion products:

  • Naturally-derived ingredients: extracted from starch
  • Fast-acting, targeted release mechanism
  • Eliminates undesirable tastes/odors
  • Controls chemical reactions and release
  • Preserves food and compound for an extended shelf life of at least 3 years, including volatile and fragile materials

APD Cyclodextrin Expertise Guarantee

At Advanced Powder Dynamics, we take pride in our proven ability to provide quality-assured cyclodextrin microencapsulated to meet specific needs:

  • Expertise and focus in product innovation
  • Faster R&D cycle
  • Effective cross-functional collaborations
Scientists in a biotech lab

Get In Touch

To learn more about our particle engineering services, contact us or call (928) 492-4040.